Voltage-gated potassium channel proteins, like Shaker are essential for transmission of nerve signals. To transmit a signal, the potassium channel opens, allowing potassium ions to cross the cell membrane. The channel then rapidly closes, which begins the process that makes the neuron ready to relay the next signal. The rapid closing of Shaker is caused by the N-terminal region of the protein entering the pore of the protein and blocking the passage of ions. Different structures have been proposed for this
Posted: 31 Jul 2019
Carbon nanotubes, graphene, and their derivatives find growing use in research, industry, medicine, and commercial products. Hence, there is an increasing need to study the behavior of these nanomaterials in living systems and the environment. In this study ( DOI: 10.1021/acs.jctc.8b00830 ) , we used molecular simulation and supplemented by analytical chemistry, to explore in detail the adsorption thermodynamics of a diverse set of aromatic compounds on graphenic materials, elucidating the effects of the so