PicoGUS can emulate Gravis UltraSound, Sound Blaster 2.0 / AdLib (OPL2), CMS/Game Blaster and Tandy 3-Voice, and supports MIDI output with MPU-401 intelligent mode emulation. It comes in two versions: the original ISA card, and the "Femto" edition that can plug into a Hand386/Book8088 or ISA adapter.
PicoGUS 2.0 is available at:
Got a PicoGUS 2.0? Read the the Getting Started with PicoGUS 2.0 wiki page!